Direct phosphonation of quinoxalin-2(1H)-ones under transition-metal-free conditions.
نویسندگان
چکیده
A direct C-H bond phosphonation of quinoxalin-2(1H)-ones with H-phosphonates, H-phosphinates or H-phosphine oxides has been developed. A wide variety of heteroaryl phosphonates were obtained in up to 92% yield for 20 examples under transition-metal-free conditions. This protocol tolerates a broad scope of substrates and features practicality, high efficiency, environmental friendliness and atom economy.
منابع مشابه
Direct regioselective phosphonation of heteroaryl N-oxides with H-phosphonates under metal and external oxidant free conditions.
A direct C-H/P-H functionalization of heteroaryl N-oxides with H-phosphonates is described. A wide variety of heteroaryl phosphonates were obtained in up to 92% yield in a chemo- and regioselective manner, under oxidant and metal free conditions. This procedure features practicality, high efficiency, environmental friendliness and atom economy.
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 13 شماره
صفحات -
تاریخ انتشار 2016